Proteinuria in Chronic Kidney Disease
Proteinuria means there is much protein in urine. In normal condition, there are less than 150mg protein in our daily urine output. While for patients with chronic kidney disease, they often have proteinuria, which means their protein loss is more than that normal volume.
Patients may have no obvious symptom if their proteinuria amount is little, and they may just find they have gotten this symptom under microscope. While as their condition progresses, some obvious symptoms will appear, like edema, foams in their urine. And because protein is an important part of our immunity, large loss of protein can also cause patient to have weak immune system, which can make patients easy to get infected.
The major causes of proteinuria is the damage in patient’s kidneys.
Kidney function is mainly completed by nephron, and nephron consists of glomerulus and kidney tubule. Glomerulus’ work is mainly completed by its two filtration membranes, so most nutrients can be kept in blood, and protein is among them. In fact, there will be some small-size proteins leaking out from glomeruli, and these will be reabsorbed by kidney tubules. For patients with proteinuria, their condition is caused by the damage in their nephrons, and then protein can not be retained in blood or reabsorbed back to blood, so patients will have proteinuria. While for patients with large amount of proteinuria, like patients with nephrotic syndrome, their condition is mainly caused by the lesion in glomeruli.
Proteinuria can aggravate patient’s kidney lesion, and it can even cause patient to have kidney failure if it has not been well controlled.
Leaked protein can accumulate in the mesangial area, which will damage this part, and as its progression, glomerular sclerosis will appear. Besides, leaked protein can also influence the enzyme of kidney tubule, and damage kidney tubule’s function.
A direct measure to treat proteinuria is to restrict protein intake. The recommended protein intake for patient with kidney disease is 0.8g/kg per day. And it is important for patient to take high-quality protein, which is essential for body health.
Besides, patients should choose treatment that can improve their kidney function, and traditional Chinese medicine is recommended, because its theory is to improve patient’s self-repairing ability to treat the disease. Nowdays, we have Micro-Chinese Medicine Osmotherapy in china, it is a external treatment of kidney disease, and it can be a great help for the improvement of kidney function.
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