Nephrotic Syndrome is a kidney disorder with heavy proteinuria, hypoalbuminemia, hyperlipemia and edema. There have no effective treatments for curing it. What we can do is to slow down its progression to kidney failure and retain the kidney function. Many doctors in the world are exploring alternative treatments for Nephrotic Syndrome. Here Pulse therapy emerges. Can it be a breakthrough in treating kidney disease?
What is pulse therapy?
Pulse therapy is a short, intensive course of pharmacotherapy, usually given at internals such as weekly or monthly to enhance the therapeutic effect and reduce side effects. It has been used successfully in preventing kidney transplant rejection and treating Lupus Nephritis. Does it have effect on Nephrotic Syndrome?
Pulse therapy for Nephrotic Syndrome
Under normal circumstance, the various options available for treatment of Nephrotic Syndrome patients include corticosteroids, levamisole, oral cyclophosphamide, chlorambucil, mechlorethamine and cyclosporin etc. They can relieve some of the symptoms, but long-term use of these side effects has many side effects. This is especially true in children. To decrease side effects, pulse therapy can be used.
Studies have proved that intravenous cyclophosphamide is a safe and effective therapeutic modality in children with idiopathic Nephrotic Syndrome when comparable with oral cyclophosphamide.
Besides, methylprednisolone pulse therapy also plays a role in inducing remission in children with steroid-resistant Nephrotic Syndrome.
Pulse therapy can be given to patients of all ages but the doses have to be reduced to half for children below the age of12 years. And each patient must receive additional appropriate treatment according to his/her own physical condition.
However, pulse therapy has not been popular in the world. Its curative effects need further validation. Nephrotic Syndrome sufferers, please do not lose hope at any time. If you have any troubles, contact us and we are glad to help you.