Lupus Nephritis is caused by SLE that is a kind of autoimmune diseases.The deposition of immune complex on glomerulus capillary epithelial cells is the key reason to Lupus Nephritis.Moreover,heredity,habitus and the environment are the important factors to the Systemic Lupus Erythematosus evolving into Lupus Nephritis. What’s more,Systemic Lupus Erythematosus (SLE) is a hereditary disease. ONLINE DOCTOR can help you get more details quickly for free.
Because most of the patients with Lupus Nephritis are women of childbearing age,many patients with their families are very concerned about how they with Lupus Nephritis can give birth to healthy baby?
Because the abortion of the female patients with SLE happen easier in the first three months of pregnancy and the patients condition may become worse in the last months and after delivery,whether female patients with LN can be pregnant is controversial.In clinic,it has been observed that most women with SLE can get married,be pregnancy and give birth to a baby when illness is alleviated basically.What’s more,if it has a certain conditions,the condition is still remissive after birth.
1.patients condition is relieved more than 6 months.
2.Anticardiolipin antibody negative. The abortion and stillbirth are easier when it is positive.
3.Take no hormone or less than 15mg of prednisone.
4.Strengthen observation and regularly follow up after pregnancy and be confined in a obstetrics of a Experienced hospital
5.Prednisone will be oxidated to inactive 11 - keto form by placenta,which can protect fetus.Thus that mothers with LN take prednisone is no influence.In order to prevent the disease be worsen in gestation period or after delivery,the dose should be increased according to the patients condition.If the disease is stable,patients can restore the original dose.
6. Dexamethasone and betamethasone are not oxidated by placenta and will influence fetus,so patients should change these two medicine to prednisone.
7.During pregnancy and breast feeding,calcium should be taken more or it will accelerate the patient osteonecrosis.
8.During breast feeding,dosage of prednisone should be keep in less than 15mg,not more than 30 mg.
9.salicylate is forbidden to pregnant woman,and the NSAIDs,antimalarial and immunosuppressor should also be stopped.
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