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How Does Kidney Biopsy Help Diagnose Lupus Nephritis

Provided by Expert Yang Hongtao on : 2013-10-29 15:13

How Does Kidney Biopsy Help Diagnose Lupus NephritisLupus Nephritis refers to kidney inflammation caused by systemic lupus erythematous (SLE). To determine the type, treatment and prognosis of Lupus Nephritis, kidney biopsy, or renal biopsy, may be needed.

What is kidney biopsy?

Kidney biopsy is a test for one sample of your kidney tissue. During this test, you will need to take off most of your clothes and then wear a gown. With the help of B ultrasound, CT scan, MRI, etc, doctors insert a thin needle into your kidney through your skin. Then, the needle is removed after the tissue sample is taken.

Through testing your kidney biopsy, doctors can confirm your suspected kidney disease, the changes of kidney tissues, treatment, etc.

How does kidney biopsy help diagnose Lupus Nephritis?

In recent years, with the improvement of renal biopsy technique, it has been used commonly in Lupus Nephritis diagnosis. According to the report of kidney biopsy, doctors can adjust the treatment plan and decide the prognosis correctly.

It indicates corticosteroids and cytotoxic drugs can help treat Lupus Nephritis, when you have the following conditions:

● Glomerular segmental necrosis

● The obvious proliferation of glomerular inherent cells

● The changes of glomerular basement membrane

● Deposits in glomerular mesangial area or endothelial area

● Cellular crescent

● Lesions in small renal blood vessels

However, if Lupus Nephritis is characterized by chronic nephropathy, the therapeutic effect is usually bad. Glomerular sclerosis, fiber crescents, renal tubular atrophy,renal interstitial fibrosis, sclerosis of renal tubule, etc, all can be our basis.

Can all Lupus Nephritis patients do this test?

Of course not, some patients are not recommended to do this test because of high risk. If you have obvious bleeding, severe hypertension, shrinking kidney, over-obesity, chronic kidney failure and some other problems, you had better stay away from kidney biopsy.

In view of this, you had better consult the doctor in detail before doing renal biopsy.


It is quite hard to fight against kidney disease for a long time. Now, a lot of kidney experts here try to give biggest help for kidney patients. If you have some questions about any kind of kidney disease, welcome to contact us by the following ways.

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