As we all know, drugs are not food, not to mention health care products, there will be certain toxic side effects, the scope of its side effects are closely related to the characteristics of the drug itself. Especially the extensive use of a large number of synthetic chemicals, resulting in a series of confusing and difficult to prevent damage, often called drug-borne diseases.
Renal damage is a clinically concerned problem at present. The use of nephrotoxic drugs in patients with kidney disease has led to a sharp deterioration of renal function. Kidney is one of the metabolic organs of drugs, and on the contrary, it is easily damaged by drugs.
Drug damage to the kidney in two ways, one is direct damage, such as nephrotoxic drugs can directly damage the renal tubules, and drug concentration related, such as sulfonamide crystals can cause kidney obstruction and other mechanical damage; the other is indirect damage, its damage in many ways; mainly allergic damage Harm, immune complex damage, hemodynamic and rheological changes, electrolyte disorders caused by damage to the kidney drugs can directly lead to renal tubular necrosis; osmotic nephropathy; nephritis or other changes in the glomerulus; obstructive nephropathy.
At the same time, for those who have renal dysfunction, such as the elderly, chronic kidney disease patients, more common is to lead to further decline in renal function. Drugs causing kidney damage mainly include analgesics, vitamin A, D penicillin, gentamicin, kanamycin, sulfonamides, amphotericin B, anti-tuberculosis drugs and other antibiotics, ether, cyclopropane, morphine, carbon monoxide and other drugs, osmotic diuretics, mercury diuretics, benzothiazole diuretics and other most improper use. Diuretics, various contrast agents, antitumor drugs, and so on.
It should be noted that some drugs are often used by patients with kidneys, such as diuretics, so should be under the guidance of doctors, avoid self-purchasing drugs, kidney disease patients had better be under the guidance of specialists.
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