Right and timely diagnosis of FSGS is the basis for patients to have an early control about this illness. Well, how to diagnosis FSGS?
FSGS is the abbreviation of Focal Segmental Glomerulosclerosis and diagnosed with renal biopsy in medicine. Renal biopsy is a medical procedure in which a tiny portion of the kidney tissue is taken out of the body for analysis. FSGS is a glomerular disease, and with renal biopsy, we can find that there are scar in glomerulus.
Glomerulus is an important part of nephron which is composed of glomerulus, renal tubule and renal capsule. In normal condition, glomerulus works as a filter through mechanism barrier and charge barrer. While blood flow through glomerulus, nutrition like protein will be kept in blood and wastes like creatinine and urea nitrogen are excreted successfully. However, for patients with FSGS, their glomeruli are injured, so when blood flow by glomeruli, protein will leak into urine and thus form proteinuria. This is the reason why FSGS patients are always detected with excess protein in urine.
Besides, renal biopsy is necessary for the diagnosis of FSGS, but for this, patients are usually suggested to do Routine Blood Test and Routine Urine Test which are the two most common tests for measuring kidney problem. With urine test, we can know if there are excess protein and red blood cell in urine. And by doing blood test, we can know clearly about serum creatinine level and BUN (Blood Urea Nitrogen) level. Through these two tests, we can calculate patient’s GFR (Glomerular Filtration Rate) which reflects how well the kidney function.
Lastly, renal biopsy is necessary for the diagnosis of FSGS, but for patients whose illness is very serious, they are usually not suggested to do this medical test as this test is harmful for kidney to some extent.