Diabetic nephropathy, also known as Kimmelstiel–Wilson syndrome, or nodular diabetic glomerulosclerosis and intercapillary glomerulonephritis, is a progressive kidney disease caused by angiopathy of capillaries in the kidney glomeruli. It is classified as a small blood vessel complication of diabetes. If you have any question please ask our ONLINE DOCTOR. We will give professional guidance as soon as possible.
Kidney failure provoked by glomerulosclerosis leads to fluid filtration deficits and other disorders of kidney function. There is an increase in blood pressure (hypertension) and fluid retention in the body plus a reduced plasma oncotic pressure causing edema. Other complications may be arteriosclerosis of the renal artery and protein in the urine.
Throughout its early course, diabetic nephropathy has no symptoms. They develop in late stages and may be a result of excretion of high amounts of protein in the urine or due to renal failure:
Swelling, usually around the eyes in the mornings; later, general body swelling may result, such as swelling of the legs; foamy appearance or excessive frothing of the urine, unintentional weight gain; poor appetite, nausea and vomiting.
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