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What Causes Diabetic Nephropathy

Provided by Expert Yang Hongtao on : 2013-10-27 15:00

What Causes Diabetic NephropathyCurrently, diabetes is the leading cause of chronic kidney disease in the world. Diabetic nephropathy is one of the most significant long-term complications in terms of morbidity and mortality for individual patients with diabetes. What on earth causes Diabetic Nephropathy? The exact cause is still unknown, but there are various postulated mechanisms:

Genetic factors

Certain ethnic groups, particularly African Americans, persons of Hispanic origin, and American Indians, may be particularly disposed to renal disease as a complication of diabetes.

High blood sugar

Prolonged exposure to high blood sugar can damage delicate nerve fibers, as a result, interfering with the their ability to transmit signals. Besides, it weakens the walls of the small blood vessels that supply the nerves with oxygen and nutrients. Over time, the kidney will not function well due to oxygen deficiency and accumulation of wastes.

High blood pressure

High blood pressure is a common symptom of diabetic nephropathy and also the important factor which attributes to the occurrence and development of this disease. When the pressure to the blood vessels is too high, it is easy to aggravate the building up of water and sodium in the cells, resulting in damage to kidneys.

High cholesterol

High cholesterol also plays a role in the progression of nephropathy. It will cause high blood pressure and atherosis, both of which are not good for kidneys.

Other factors

There are also many daily details which may cause diabetic nephropathy:

-Smoking and drinking abuse


-Too much intake of sodium

-Lack of exercise

-Great psychological pressure

From the above, we can know that diabetic nephropathy is caused by many factors. Therefore, it is necessary for you to make a comprehensive examination to define your own causes and then find specific ways to treat diabetic nephropathy.

If you are diagnosed with diabetic nephropathy, we are always here to help you. Consulting our online doctors or leaving us a message are both OK. Best wishes!



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