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Creatinine Over 400 Enters Into Kidney Failure 4 Stage

Provided by Expert Yang Hongtao on : 2019-02-24 10:05

Kidney Failure 4 Stage,Creatinine Over 400,CreatinineAt the beginning of nephropathy, the pathological changes of the kidney are mild, which may be asymptomatic hematuria or asymptomatic proteinuria, or nephrotic syndrome or nephritis syndrome with obvious proteinuria, hematuria, edema and hypertension.

Patients with milder illness take Chinese patent medicine, pril/sartan and other drugs, and more importantly, use hormones, immunosuppressive agents, and even rituximab, infliximab, plasma exchange and other methods.

Their condition is not well controlled, the condition is good or bad, the kidney has been in the state of inflammation, the necrosis, sclerosis and fibrosis of kidney cells are quietly proceeding.

Thereafter, the quality of life of nephrotic patients was quite different from that of the first half of life.

Firstly, cystatin C exceeded the standard, suggesting that renal function was impaired, then serum creatinine and urea nitrogen began to rise, and renal function decreased at a rate of 3% - 5% per year. When serum creatinine exceeded 200 micromol/L, renal anemia and renal hypertension occurred in succession.

After creatinine exceeded 400 micromol/L, electrolyte, acid-base balance, cardiac function and other abnormalities occurred, complications occurred frequently, and renal failure accelerated.

When more than 90% of the kidney function was lost, the kidney disease progressed to the fifth stage. Under the threat of serious complications such as heart failure, hyperkalemia and acidosis, dialysis began.

Dialysis can replace part of the detoxification capacity of the kidney, but the body is still under the cover of high blood pressure, anemia and high toxin levels. Most uremic patients died of cardiovascular complications, severe infections, cerebrovascular accidents, gastrointestinal bleeding and hyperkalemia after dialysis for 10 to 20 years. The average life expectancy was about 65 years.

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