Henoch-Schonlein Purpura Nephritis (HSPN) is a systemic small vessel damage. In addition to the clear symptoms of skin, any tissue or organ with small vessels may be one of the target organs of damage. Kidney is a small vessel-rich organ. Half of HSPN affects the kidney, leading to Henoch-Schonlein purpura nephritis.
In children, the incidence of Henoch-Schonlein purpura nephritis caused by purpura averaged 45%, while in adults, the incidence was relatively high, averaging about 63%. However, the incidence of Henoch-Schonlein purpura in children is much higher than that in adults. 90% of the children are 7-13 years old. If the rash lasts for more than one month or recurs repeatedly, the senior children, accompanied by gastrointestinal bleeding or arthritis are easy to involve the kidney. The monitoring of kidney damage should be strengthened in these patients, and more of these patients should go to the nephrology department.
How long will Henoch-Schonlein purpura nephritis occur after the occurrence of Henoch-Schonlein purpura?
The vast majority of patients with skin purpura, kidney damage 4 weeks later, 3.4% - 20% of the rash occurred 3 months or even 3 years before the occurrence of kidney damage. Very few cases can be characterized by kidney damage first, and typical skin purpura occurs only for months or even years, often misdiagnosed as igA nephropathy.
Will Henoch-Schonlein purpura nephritis cause permanent kidney damage, lead to uremia, and endanger life?
If untreated, renal hyperplasia and aging of the crescent of the globe will lead to permanent kidney damage, repeated attacks, part of the permanent kidney damage, which will lead to uremia. Most purpura nephritis does not endanger life, but some patients with gastrointestinal hemorrhage or cerebral hemorrhage, or infection after using immunosuppressive agents, may also endanger life.
Can Henoch-Schonlein purpura nephritis be completely cured?
Early detection, mild lesions, no repeated allergies, may be completely cured.
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